of Pharmaceutical , Biological and Chemical Sciences Pharmacochemical Characterization , FT - IR and Antibacterial Activity of Vernonia Cinerea Less

The present study has been carried out to evaluate the pharmacochemical characterization and in vitro antibacterial activity of the whole plant extracts of Vernonia cinerea. Physicochemical parameters (Ash value and extractive value; fluorescence analysis) and phytochemical analysis were done by using the standard methods. FT-IR analysis of V. cinerea was carried out.The petroleum ether, chloroform, acetone, methanol and ethanol extracts were tested against Pseudomonas aeruginosa, Streptococcus pyogenes, Streptococcus faecalis and Salmonella paratyphi by the agar disc diffusion method. The total ash value of whole plant of V. cinerea is 11.34%. The extractive value of water is more than in the solvents investigated. Preliminary photochemical screening of whole plant showed the presence of alkaloid, anthraquinone, coumarin, phenol tannin, glycoside, xanthoprotein, and sugar. From the spectral data of FT-IR, presence of C=O, C-H, C=O, C-O, C-C, were identified. The whole plant extracts of V. cinerea showed potent antibacterial activity against both Gram positive and negative bacteria. The pharmacochemical characterization will be helpful to study the active principles using modern techniques in the later part of this work.